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Mannitol 2-dehydrogenase
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Mannitol 2-dehydrogenase : ウィキペディア英語版
Mannitol 2-dehydrogenase

In enzymology, a mannitol 2-dehydrogenase () is an enzyme that catalyzes the chemical reaction
:D-mannitol + NAD+ \rightleftharpoons D-fructose + NADH + H+
Thus, the two substrates of this enzyme are D-mannitol and NAD+, whereas its 3 products are D-fructose, NADH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is D-mannitol:NAD+ 2-oxidoreductase. Other names in common use include D-mannitol dehydrogenase, and mannitol dehydrogenase. This enzyme participates in fructose and mannose metabolism.
==Structural studies==

As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes and .

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